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银杏叶片联合阿立哌唑治疗精神分裂症的疗效的影响分析 |
Analysis of the therapeutic effect of Ginkgo biloba leaves combined with aripiprazole in the treatment of schizophrenia and the influence of miR-155 and NRG-1 levels |
投稿时间:2024-09-24 修订日期:2024-09-24 |
DOI: |
中文关键词: 阿立哌唑 银杏叶片 精神分裂症 疗效 |
英文关键词: Aripiprazole Ginkgo biloba leaves Schizophrenia Therapeutic effect |
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中文摘要: |
【摘要】目的:分析银杏叶片联合阿立哌唑治疗精神分裂症的疗效。方法:研究纳入医院2021年8月-2022年8月临床收治精神分裂症患者80例为对象,数字抽签分组为对照组(n=40)与研究组(n=40),分别采用阿立哌唑、银杏叶片联合阿立哌唑连续治疗5周,比较组间阴性与阴性症状量表(PANSS)、疗效、重复性成套神经心理态度测验(RBANS)评分。结果:治疗前,组间PANSS无统计学差异(P>0.05),研究组治疗1周、3周及5周后PANSS均低于对照组(P<0.05);研究组治疗有效率高于对照组(χ2=3.914,P<0.05);治疗前,组间RBANS评分无统计学意义(P>0.05),研究组治疗5周后RBANS高于对照组(P<0.05)。结论:银杏叶片联合阿立哌唑能提升精神分裂症临床疗效,改善患者神经状态及认知功能。 |
英文摘要: |
[Abstract] Objective: To analyze the curative effect of ginkgo biloba leaf combined with aripiprazole in the treatment of schizophrenia. Method: A total of 80 patients with schizophrenia admitted to the hospital from August 2021 to August 2022 were included in the study. They were divided into control group (n=40) and study group (n=40) by numerical lottery. They were treated with aripiprazole, ginkgo leaf combined with aripiprazole for 5 weeks, respectively. The intergroup Negative and negative Symptom Scales (PANSS), efficacy, and repeated neuropsychological attitude battery test (RBANS) scores were compared. Result: Before treatment, there was no significant difference in PANSS between groups (P > 0.05), and PANSS in the study group was lower than that in the control group after 1, 3 and 5 weeks of treatment (P < 0.05). The effective rate of the study group was higher than that of the control group (χ2=3.914, P < 0.05). Before treatment, RBANS scores were not statistically significant between groups (P>0.05), and RBANS in the study group were higher than those in the control group after 5 weeks of treatment (P < 0.05). Conclusion: Ginkgo biloba combined with aripiprazole can improve the clinical efficacy of schizophrenia and improve the neurological status and cognitive function of patients. |
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