| Paclitaxel for injection (albumin-bound) is now widely used in the treatment of a variety of solid tumors; However, there is no standard treatment for peripheral nerve toxicity caused by sufficient doses of paclitaxel (albumin-binding type), which may lead to dose reduction or no further treatment. Professor Zhang Mei analyzed from TCM syndrome differentiation that paclitaxel (albumin-binding type) is a cold toxin. The etiology and pathogenesis of peripheral nerve toxicity caused by paclitaxel is cold toxin invading the body, causing blood deficiency and cold coagulation, and stasis blocking the vein; So to warm Yang Tongluo, tonifying qi and blood, tonifying liver and kidney as the treatment principle, and apply the above theory to guide clinical practice. Wenyang Tongluo prescription (Duhuashi Decoction as the basis to remove licorice, ginseng, cinnamon plus astragalus, Shenjincao, Luoshiteng, Radix japonicae, attached tablets, codonopsis, cassia twig) treatment of paclitaxel (albumin-binding type) induced peripheral nerve toxicity, alleviate cold, numbness, tingling discomfort, improve quality of life; Escort for anti-tumor therapy. |
