文章摘要
滋肾调肝活血法治疗对不同月经时期PCOS的干预价值
The Intervention Value of Nourishing Kidney, Regulating Liver and Activating Blood Treatment on PCOS in Different Menstrual Periods
投稿时间:2020-12-28  修订日期:2020-12-28
DOI:
中文关键词: 滋肾调肝活血法  多囊卵巢综合症  月经周期  肝郁肾虚证
英文关键词: Zishen tiaogan Huoxue Method  Polycystic ovary syndrome  Menstrual cycle  Liver depression and kidney deficiency syndrome
基金项目:1.基金项目:宁波市科技计划自然基金项目,课题名称:滋肾调肝活血调周法重建多囊卵巢综合症患者月经周期节律及对糖脂代谢的影响,编号:2016A610201 2.基金项目:宁波市科技计划重点学科项目,课题名称:滋肾调肝活血调周法对PC0S患者糖脂代谢及炎症相关因子的影响研究,编号:2016ZB112
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中文摘要:
      目的 研究基于不同月经时期应用滋肾调肝活血法治疗对多囊卵巢综合征(PCOS)的干预价值。方法 选取2017年10月到2019年10月在我院接受治疗的PCOS患者90例作为研究对象,按照随机数字表法将其随机分为观察组和对照组,每组45例,对照组口服达英-35治疗,观察组在对照组基础上对患者不同月经时期进行滋肾调肝活血法治疗,比较两组临床疗效,比较两组治疗前后雌性激素分泌[卵泡刺激素(FSH)、黄体生成素(LH)、睾酮(T)]、中文版PCOS患者生活质量量表(MPCOQS)评分,另比较两组不良反应发生情况。结果 观察组临床疗效总有效率为84.44%显著高于对照组64.44%,差异有统计学意义(P<0.05)。观察组治疗后LH、T水平显著低于治疗前及对照组治疗后,差异有统计学意义(P<0.05)。观察组治疗后多毛症、肥胖、痤疮、不孕、月经失调评分显著低于治疗前及对照组治疗后,差异有统计学意义(P<0.05)。观察组不良反应总发生率为26.67%,与对照组20.00%比较,差异无统计学意义(P>0.05)。结论 基于不同月经时期应用滋肾调肝活血法可显著改善PCOS患者临床症状,改善其雌性激素分泌,且安全性良好,临床价值较高。
英文摘要:
      Objective To study the intervention value of Zishen tiaogan Huoxue therapy on polycystic ovary syndrome (PCOS) based on different menstrual periods. Methods 90 cases of PCOS patients who were treated in our hospital from October 2017 to October 2019 were selected as the research objects, and they were randomly divided into observation group and control group, 45 cases in each group,The control group was treated with Diane-35 orally, while the observation group was treated with nourishing kidney, regulating liver and activating blood circulation on the basis of the control group,The clinical efficacy was compared between the two groups, and the scores of female hormone secretion [follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T)] and Chinese version of PCOS quality of life scale (mpcoqs) scores were compared between the two groups before and after treatment, and the incidence of adverse reactions between the two groups was compared. Results The total effective rate of the observation group was 84.44%, which was significantly higher than that of the control group (64.44%) (P < 0.05).The levels of LH and T in the observation group were significantly lower than that before and after the control group (P < 0.05).After treatment, the scores of hirsutism, obesity, acne, infertility and menstrual disorders in the observation group were significantly lower than those before and after treatment in the control group, and the difference was statistically significant (P < 0.05).The total incidence of adverse reactions in the observation group was 26.67%, compared with 20.00% in the control group, the difference was not statistically significant (P > 0.05).Conclusion Based on different menstrual periods, Zishen tiaogan Huoxue method can significantly improve the clinical symptoms of PCOS patients, improve the secretion of estrogen, and has good safety and high clinical value.
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