文章摘要
芒硝外敷联合维生素E对非酒精性脂肪肝患者血清瘦素水平的影响
Effects of application of glauber's salt combined with vitamine E on serum leptin levels in patients with nonalcoholic fatty liver disease
投稿时间:2019-10-20  修订日期:2019-10-20
DOI:
中文关键词: 芒硝  非酒精性脂肪肝  瘦素
英文关键词: glauber's salt,nonalcoholic fatty liver disease,leptin
基金项目:2018年湖州市科技局科技计划项目(编号2018GY69)
作者单位E-mail
魏君雄 安吉县第三人民医院 89450937@qq.com 
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中文摘要:
      目的:观察芒硝外敷联合维生素E对非酒精性脂肪肝患者的治疗疗效和对血清瘦素水平的影响。方法:治疗组对照组各30例,分别采用芒硝外敷联合维生素E治疗和单用维生素E治疗,疗程3个月,观察患者的临床疗效和血清瘦素水平的变化。结果:治疗组疗效93.33%,对照组疗效70.00%,治疗组疗效明显优于对照组;治疗后两组症状积分均显著降低,且治疗组较对照组降低明显;治疗后两组患者 TC、TG、LEP 比较,治疗组降低明显,差异均有统计学意义(P<0.05 或 P<0.01)。结论:芒硝外敷联合维生素E治疗非酒精性脂肪肝患者取得了较好的临床疗效,其作用机理可能与减少脂肪吸收、改善血清瘦素抵抗、影响血脂代谢等作用有关。
英文摘要:
      Objective:to observe the effect of application of glauber's salt combined with vitamine E on serum leptin levels in patients with nonalcoholic fatty liver disease.Methods:30cases in each of the treatment group and control group were treated with glauber's salt plus viamine E and vitamine E alone for 3 months.Results:the curative effect of teratment group was 93.33%,the curative effect of control group was 70.00%.the curative effect of treatment group was obviously superior to the control group,After treatment, the clinical symptom score significantly decreased in both groups, and the therapeutic effect of the treatment group was superior to that in the control group.After treatment,level of TC、TG and LEP significantly reduced in both groups, and the therapeutic effect of the treatment group was superior to that in the control group(P<0.05 or P<0.01)。Conclusion: application of glauber's salt combined with vitamine E in patients with nonalcoholic fatty liver disease has achieved good clinic efficacy,and its mechanism may be related to reducuing fat absorption,improving leptin resistance and effecting lipid metabolism.
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