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| 柴芩温胆汤治疗乳腺癌失眠患者的疗效观察 |
| Observation of Efficacy of Chai Qing Wen Dan Decoction in Breast Cancer Patients with Insomnia |
| 投稿时间：2025-01-17 修订日期：2025-01-17 |
| 中文关键词: 柴芩温胆汤 乳腺癌 失眠 |
| 英文关键词: Chai Qing Wen Dan Decoction,Breast Cancer,Insomnia |
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| 中文摘要: |
| 目的：观察柴芩温胆汤加减治疗乳腺癌失眠的临床疗效。方法：选取 2022年1月—2024 年10月在浙江省东阳市中医院门诊治疗的 60 例失眠患者，采用随机数字表法分为 观察组与 对照组，每组 30 例。对照组应用艾司唑仑治疗，观察组应用柴芩温胆汤加减治疗。两组均治疗3周。比较两组治疗前后PSQI评分和中医证候积分。结果：治疗前两组中医证候积分比较，差异无统计学意义（P ＞ 0.05）；治疗后两组中医证候积分均低于治疗前，且 观察组各项中医证候积分均低于对照组，差异有统计学意义（P ＜ 0.05）。治疗前两组匹兹堡睡眠质量指数（PSQI）评分比较，差异无统计学意义（P ＞ 0.05）；治疗后，两组 PSQI 评分均低于治疗前，且 治疗组 PSQI 评分低于对照组，差异有统计学意义（P ＜ 0.05）。结论：柴芩温胆汤加减治疗肝郁痰热型乳腺癌失眠的效果显著，在改善患者的睡眠质量同时缓解其临床症状。 |
| 英文摘要: |
| Objective: To observe the clinical efficacy of modified Chaihu Wen Dan Tang in the treatment of insomnia in breast cancer patients. Methods A total of 60 patients with insomnia treated in the outpatient department of Dongyang Traditional Chinese Medicine Hospital in Zhejiang Province from January 2022 October 2024 were selected. The patients were divided into the observation group and the control group using the randomized numerical table method, with 30 cases each group. The control group was treated with eszopiclone, and the observation group was treated with modified Chaihu Wen Dan Tang. Both groups were for 3 weeks. The PSQI scores and traditional Chinese medicine (TCM) syndrome scores before and after treatment were compared between the two groups. Results: was no significant difference in the TCM syndrome scores between the two groups before treatment (P > 0.05). After treatment, the TCM syndrome scores both groups were lower than those before treatment, and the scores of each TCM syndrome in the observation group were lower than those in the control group, with a significant (P < 0.05). There was no significant difference in the PSQI scores between the two groups before treatment (P > 0.0). After treatment, the PSQI scores of both groups were lower than those before treatment, and the PSQI scores of the treatment group were lower than those of the control group, with a significant difference (P < 0.05). Conclusion: The modified Chaihu Wen Dan Tang has a significant effect on the treatment insomnia in breast cancer patients with liver depression and phlegm-heat, which not only improves the patients'' sleep quality but also relieves their clinical symptoms |
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