|
| 金水通窍方联合盐酸坦索罗辛治疗良性前列腺增生的临床疗效及对前列腺功能、尿流动力学的影响 |
| Clinical Efficacy of Jinshui Tongqiao Formula Combined with Tamsulosin in the Treatment of Benign Prostatic Hyperplasia and Its Impact on Prostate Function and Urodynamics |
| 投稿时间：2024-11-29 修订日期：2024-11-29 |
| DOI： |
| 中文关键词: 良性前列腺增生 盐酸坦索罗辛 金水通窍方 前列腺功能 尿流动力学 |
| 英文关键词: Benign prostatic hyperplasia Tamsulosin Jinshui Tongqiao Formula Prostate function Urodynamics |
| 基金项目: |
| 摘要点击次数: 40 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的 观察金水通窍方联合盐酸坦索罗辛治疗良性前列腺增生(BPH)的临床疗效及对前列腺功能、尿流动力学的影响。方法 选取2023年1月至2024年1月期间96例BPH患者,采用随机数字表法分为观察组、对照组各48例,对照组接受盐酸坦索罗辛缓释胶囊治疗,观察组在对照组相同治疗的基础上加用金水通窍方,均连续治疗12周。比较两组临床疗效,治疗前后症状积分、国际前列腺症状评分(IPSS)、国际勃起功能指数简表-5(IIEF-5)及尿流动力学(最大逼尿肌压力、最大尿流率、膀胱残余尿量)。结果 治疗12周后,观察组总有效率高于对照组(P＜0.05)；两组排尿困难、尿频、尿急、尿道灼热感、尿线中断评分,IPSS评分及最大逼尿肌压力、膀胱残余尿量均较治疗前降低(P＜0.05),且观察组均低于对照组(P＜0.05)；两组IIEF-5评分、最大尿流率均较治疗前提高(P＜0.05),且观察组高于对照组(P＜0.05)。结论 金水通窍方联合盐酸坦索罗辛治疗BPH可显著改善患者临床症状,提高前列腺功能,改善尿流动力学指标,疗效优于单纯应用盐酸坦索罗辛。 |
| 英文摘要: |
| Objective To observe the clinical efficacy of Jinshui Tongqiao Formula combined with tamsulosin in the treatment of benign prostatic hyperplasia (BPH) and its impact on prostate function and urodynamics. Methods A total of 96 BPH patients treated from January 2023 to January 2024 were selected and randomly divided into observation and control groups, with 48 patients in each group. The control group received tamsulosin sustained-release capsules, while the observation group was additionally treated with Jinshui Tongqiao Formula on the basis of the control group. Both groups were treated continuously for 12 weeks. The clinical efficacy, symptom scores, International Prostate Symptom Score (IPSS), International Index of Erectile Function-5 (IIEF-5), and urodynamic parameters (maximum detrusor pressure, maximum urinary flow rate, and post-void residual urine volume) were compared between the two groups before and after treatment. Results After 12 weeks of treatment, the total effective rate in the observation group was significantly higher than that in the control group (P < 0.05). Scores for voiding difficulty, urinary frequency, urinary urgency, burning sensation in the urethra, and interrupted urinary flow, IPSS scores, maximum detrusor pressure and post-void residual urine volume were significantly reduced in both groups compared to baseline (P < 0.05), with lower scores in the observation group than in the control group (P < 0.05). IIEF-5 scores and maximum urinary flow rate significantly improved in both groups (P < 0.05), with higher scores in the observation group (P < 0.05). Conclusion Jinshui Tongqiao Formula combined with tamsulosin significantly improves clinical symptoms, enhances prostate function, and improves urodynamic parameters in patients with BPH, demonstrating superior efficacy compared to tamsulosin alone. |
|
View Fulltext
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
