|
| 银杏叶片联合阿立哌唑治疗精神分裂症的疗效的影响分析 |
| Analysis of the therapeutic effect of Ginkgo biloba leaves combined with aripiprazole in the treatment of schizophrenia and the influence of miR-155 and NRG-1 levels |
| 投稿时间：2024-09-24 修订日期：2024-09-24 |
| DOI： |
| 中文关键词: 阿立哌唑 银杏叶片 精神分裂症 疗效 |
| 英文关键词: Aripiprazole Ginkgo biloba leaves Schizophrenia Therapeutic effect |
| 基金项目: |
| 摘要点击次数: 109 |
| 全文下载次数: 0 |
| 中文摘要: |
| 【摘要】目的：分析银杏叶片联合阿立哌唑治疗精神分裂症的疗效。方法：研究纳入医院2021年8月-2022年8月临床收治精神分裂症患者80例为对象，数字抽签分组为对照组（n=40）与研究组（n=40），分别采用阿立哌唑、银杏叶片联合阿立哌唑连续治疗5周，比较组间阴性与阴性症状量表(PANSS)、疗效、重复性成套神经心理态度测验（RBANS）评分。结果：治疗前，组间PANSS无统计学差异（P＞0.05），研究组治疗1周、3周及5周后PANSS均低于对照组（P＜0.05）；研究组治疗有效率高于对照组（χ2=3.914，P＜0.05）；治疗前，组间RBANS评分无统计学意义（P>0.05），研究组治疗5周后RBANS高于对照组（P＜0.05）。结论：银杏叶片联合阿立哌唑能提升精神分裂症临床疗效，改善患者神经状态及认知功能。 |
| 英文摘要: |
| [Abstract] Objective: To analyze the curative effect of ginkgo biloba leaf combined with aripiprazole in the treatment of schizophrenia. Method: A total of 80 patients with schizophrenia admitted to the hospital from August 2021 to August 2022 were included in the study. They were divided into control group (n=40) and study group (n=40) by numerical lottery. They were treated with aripiprazole, ginkgo leaf combined with aripiprazole for 5 weeks, respectively. The intergroup Negative and negative Symptom Scales (PANSS), efficacy, and repeated neuropsychological attitude battery test (RBANS) scores were compared. Result: Before treatment, there was no significant difference in PANSS between groups (P > 0.05), and PANSS in the study group was lower than that in the control group after 1, 3 and 5 weeks of treatment (P < 0.05). The effective rate of the study group was higher than that of the control group (χ2=3.914, P < 0.05). Before treatment, RBANS scores were not statistically significant between groups (P>0.05), and RBANS in the study group were higher than those in the control group after 5 weeks of treatment (P < 0.05). Conclusion: Ginkgo biloba combined with aripiprazole can improve the clinical efficacy of schizophrenia and improve the neurological status and cognitive function of patients. |
|
View Fulltext
查看/发表评论 下载PDF阅读器 |
| 关闭 |
