文章摘要
膈下逐瘀汤加减对胆囊炎患者中医证候积分及胃肠道功能的影响
Effect of the addition and subtraction of subdiaphragmatic decoction on TCM syndrome score and gastrointestinal function in patients with cholecystitis
投稿时间:2024-02-27  修订日期:2024-02-27
DOI:
中文关键词: Effect of the addition and subtraction of subdiaphragmatic decoction on TCM syndrome score and gastrointestinal function in patients with cholecystitis
英文关键词: Diaphragmatic stasis decoction  Cholecystitis  TCM Syndrome Points  Gastrointestinal function
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中文摘要:
      目的 分析膈下逐瘀汤加减对胆囊炎患者疗效、中医证候积分及胃肠功能的影响。方法 回顾性选取2021年2月-2023年2月我院收治的胆囊炎患者临床资料,选取其中59例采用膈下逐瘀汤加减+常规西药治疗的作为观察组,依据配对原则1:1选取常规西药治疗的作为对照组,共118例作为本研究对象。比较两组临床疗效、胆囊壁厚度、中医证候积分、空腹胆囊容积、胃泌素(GAS)、餐后胆囊容积、血管活性肠肽(VIP)、胆囊收缩功能、胃动素(MTL)、生长抑素(SS)、不良反应。结果 治疗后观察组临床疗效(96.61%)高于对照组(83.05%),差异有统计学意义(P<0.05);治疗后观察组胆囊收缩功能水平高于对照组,胆囊壁厚度、空腹及餐后胆囊容积水平低于对照组,差异有统计学意义(P<0.05);与对照组相比,治疗后观察组VIP、中医证候积分、SS水平较低,MTL、GAS水平较高,差异有统计学意义(P<0.05)。结论 膈下逐瘀汤加减治疗可减轻胆囊炎患者临床症状,促进胆囊功能恢复,改善胃肠道功能。
英文摘要:
      Objective To analyze the effects of the addition and subtraction of subdiaphragmatic Zhuyu decoction on the efficacy, TCM syndrome score and gastrointestinal function of patients with cholecystitis.  Methods The clinical data of patients with cholecystitis admitted to our hospital from February 2021 to February 2023 were retrospectively selected, and 59 cases treated with subdiaphragmatic zhuyu decoction + conventional western medicine were selected as the observation group, and 118 cases were selected as the control group according to the pairing principle of 1:1. The clinical efficacy, gallbladder wall thickness, TCM syndrome score, fasting gallbladder volume, gastrin (GAS), postprandial gallbladder volume, vasoactive intestinal peptide (VIP), gallbladder contractile function, motilin (MTL), somatostatin (SS) and adverse reactions were compared between the two groups.  Results After treatment, the clinical efficacy of the observation group (96.61%) was higher than that of the control group (83.05%), and the difference was statistically significant(P<0.05); the level of gallbladder contractile function in the observation group was higher than that of the control group, and the level of gallbladder wall thickness, fasting and postprandial gallbladder volume was lower than that of the control group, and the difference was statistically significant(P<0.05). The difference was statistically significant (P<0.05). Conclusion The addition and subtraction of subdiaphragmatic decoction can alleviate the clinical symptoms of cholecystitis, promote the recovery of gallbladder function, and improve gastrointestinal function.
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