文章摘要
独活寄生汤加减联合运动疗法治疗继发性脊髓损伤的疗效观察
Clinical observation of Duhuo Jisheng decoction combined with exercise therapy in the treatment of secondary spinal cord injury
投稿时间:2022-07-26  修订日期:2022-07-26
DOI:
中文关键词: 独活寄生汤  运动疗法  继发性脊髓损伤  感觉运动评分  诱发电位  疗效观察
英文关键词: Duhuojisheng Decoction  Exercise therapy  Secondary spinal cord injury  Sensory motor score  Evoked potential  Curative effect observation
基金项目:浙江省中医药科技计划项目(2020ZB107),浙江省医药卫生科技计划项目(2020KY676)
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中文摘要:
      目的:观察独活寄生汤加减联合运动疗法治疗继发性脊髓损伤的疗效,收集治疗前后数据并进行讨论分析。方法:选择2016年8月至2021年8月浙江中医药大学附属第二医院骨科收治的因胸腰椎骨折导致脊髓损伤的患者64例,在手术解除脊髓压迫后予康复训练。将符合纳入标准的患者随机分为对照组和实验组两组,每组各32人。对照组患者采用单纯运动疗法治疗,实验组在此基础上加用中药独活寄生汤进行治疗。共治疗8周,比较两组治疗前后JOA、感觉、运动评分,以及躯体感觉诱发电位(somatosensory evoked potentials,以下简称SEP)和运动诱发电位(motor evoked potentials,以下简称MEP)潜伏期变化。结果:实验组的临床有效率显著高于对照组(P<0.05);相较治疗前,治疗8周后两组患者的感觉、运动评分均明显提高(P<0.01或P<0.05),且实验组优于对照组(P<0.01)。治疗后两组患者SEP、MEP的潜伏期均明显缩短(P<0.01或P<0.05),且实验组优于对照组(P<0.01)。结论:独活寄生汤加减具有辨证灵活、针对病机的优点,可谓对证施治,所以联合运动疗法综合康复所取得的疗效要显著优于单纯运动疗法的患者,因此在继发性脊髓损伤的治疗上具有重要价值,值得推广。
英文摘要:
      Abstract: [Objective] Objective To observe the curative effect of DuhuoJisheng Decoction in the treatment of secondary spinal cord injury. [Methods] From August 2014 to August 2019, 64 patients with spinal cord injury caused by thoracolumbar fractures were selected from the Department of orthopedics, the Second Affiliated Hospital of Zhejiang University of traditional Chinese medicine. They were given rehabilitation training after the spinal cord compression was relieved. The patients who met the inclusion criteria were randomly divided into control group and experimental group, 32 in each group. The control group was treated with simple exercise therapy, and the experimental group was treated with Duhuo Jisheng decoction. After 8 weeks of treatment, the clinical effective rate, sensory and motor scores, somatosensory evoked potential and motor evoked potential latency were compared between the two groups. [Results] The clinical effective rate of the experimental group was significantly higher than that of the control group (P < 0.05); the sensory and motor scores of the two groups were significantly improved after 8 weeks of treatment (P < 0.01 or P < 0.05), and the experimental group was better than the control group (P < 0.01). After treatment, the latency of SEP and MEP in the two groups were significantly shortened (P < 0.01 or P < 0.05), and the experimental group was better than the control group (P < 0.01). [Conclusion] DuhuoJisheng Decoction has the advantages of flexible syndrome differentiation, aiming at the pathogenesis, which can be said to be the treatment for the root cause. Therefore, the curative effect of combined rehabilitation training is significantly better than that of patients with simple exercise therapy. Therefore, it has important value in the treatment of secondary spinal cord injury and is worth promoting.
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