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| 引阳入阴推拿法联合揿针对围绝经期失眠患者神经内分泌水平的影响 |
| Yinyangruyin combined with intradermal needling on neuroendocrine level in patients with perimenopausal insomnia |
| 投稿时间：2020-06-15 修订日期：2020-06-15 |
| DOI： |
| 中文关键词: 推拿 揿针 围绝经期失眠 神经内分泌 |
| 英文关键词: manipulation intradermal needling perimenopause insomnia neuroendocrine |
| 基金项目: |
| 摘要点击次数: 461 |
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| 中文摘要: |
| 目的：探讨引阳入阴推拿联合揿针治疗对围绝经期失眠患者神经内分泌水平的影响。方法：随机将60例处于围绝经期的失眠患者平均分为观察组和对照组。观察组采用引阳入阴推拿联合揿针疗法,对照组予以艾司唑仑,两组均1周为1疗程,连续治疗3个疗程。比较两组治疗前后匹兹堡睡眠质量指数(PSQI)、血清雌激素(E2)、5-羟色胺(5-HT)和去甲肾上腺素(NE)含量。结果：两组治疗后PSQI评分较治疗前均显著下降(P＜0.05),观察组明显优于对照组(P＜0.05)；两组治疗后血清E2、5-HT含量均有不同程度的提高,NE有不同程度的下降(P＜0.05),且观察组血清E2、5-HT的含量明显高于对照组,NE含量对比对照组(均P＜0.05)较低；观察组与对照组在进行治疗后,前者的有效率是96.7%,而后者为80.0%(P＜0.05),观察组有效率明显高于对照组。结论：引阳入阴推拿联合揿针能够明显调节神经内分泌水平,提高处于围绝经期患者的睡眠质量。 |
| 英文摘要: |
| Objective: To explore Manipulation of Yinyangruyin combined with intradermal needling on the efficacy of neuroendocrine level in patients with perimenopausal insomnia. Methods: Sixty patients were randomized into an observation group and a control group, 30 cases in each one. In the observation group, Manipulation of Yinyangruyin combined with intradermal needling were adopted. Estazolam was applied in the control group for 3 courses,1 weeks as 1 course. The scores of Pittsburgh sleep quality index (PSQI), the levels of serum estrogen (E2), 5-hydroxy tryptamine (5-HT) and norepinephrine (NE) were valuated in the two groups before and after treatment. Results: After treatment, the total scores of PSQI reduced in the two groups (P＜0.05), and the improvements of PSQI score in the observation group were superior to those in the control group (P＜0.05). After treatment, ,E2,5-HT contents increased and NE levels decreased in the two groups (P＜0.05), with better results in the observation group (P＜0.05). The total effective rate was 96.7% in the observation group, which was higher than 80.0% in the control group (P＜0.05). Conclusion: Manipulation of Yinyangruyin combined with intradermal needling can adjust the neuroendocrine level, improve the sleep quality of patients with perimenopausal insomnia. |
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